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Extensively drug-resistant tuberculosis,while harder to treat because some antibiotics are ineffective,has a similar prognosis and recovery rate compared to nonresistant tuberculosis.

A) True
B) False

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The major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is ________.


A) its capsules
B) metachromatic granules
C) an exotoxin
D) endospores
E) an endotoxin

F) A) and C)
G) A) and B)

Correct Answer

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Legionella pneumophila ________.


A) is easily killed by chlorine
B) often lives intracellularly in amoebas
C) is transmitted through the soil
D) always causes a severe pneumonia
E) is a gram-positive bacterium

F) B) and E)
G) A) and E)

Correct Answer

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B

A 45-year-old female presents to the emergency department. She reports the onset of a sore throat, cough and rhinorrhea about five days ago. She is now experiencing weakness in her arms and difficulty breathing. She is evaluated in the emergency room and admitted to the intensive care unit. In the provider's initial assessment, the patient is noted to have gross inflammation of her pharynx and tonsils, with grayish-white patches in the pharynx. A throat swab and additional specimens are sent for microbial analysis. The patient is placed in isolation. -The nurse assesses the patient's medical history and notes that she has not received routine medical screening and treatment in the past 15 years. This patient could avoided this preventable disease by staying current with which vaccination?  


A) MMR
B) Influenza
C) Td
D) HPV

E) A) and B)
F) A) and D)

Correct Answer

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Influenza virus can exhibit constant mutation of viral glycoproteins called ________,or ________,a more serious phenomenon caused by the exchange of a viral gene with that of another influenza virus strain.


A) antigenic shift,antigenic drift
B) antigenic drift,antigenic shift
C) None of these are correct.

D) None of the above
E) B) and C)

Correct Answer

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The main contributing factor to the evolution of MDR-TB is ________.


A) the slow growth of Mycobacterium tuberculosis requires antibiotic therapy for months rather than days,which is hard to sustain in some populations; cutting the regimen short allows the resistant bacteria to flourish
B) the organisms that develop multidrug resistance have a different cell wall composition to the drug-susceptible organisms
C) certain species of Mycobacterium tuberculosis are able to undergo bacterial transformation at a faster rate than other species,resulting in the transfer of resistance genes
D) the abundance of antibiotics available in the United States and other developed countries makes it a particular problem for resistant strains to emerge in those parts of the world

E) B) and C)
F) A) and C)

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A

Which of the following is not true of whooping cough?


A) Secondary infections can occur during the convalescent phase
B) Caused by a small gram-positive rod
C) Incubation period is 3-21 days
D) Coldlike symptoms are common for the paroxysmal stage
E) An uncontrollable cough occurs during the paroxysmal stage

F) A) and C)
G) B) and C)

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Virulence factors of Streptococcus pyogenes include ________.


A) polysaccharides on the cell wall
B) lipoteichoic acid
C) M proteins
D) hyaluronic acid capsule
E) All of the choices are correct.

F) B) and D)
G) D) and E)

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When the centers of tubercles break down into ________ lesions,they gradually heal by calcification that replaces normal lung tissue.


A) primary
B) secondary
C) necrotic caseous
D) granuloma
E) tertiary

F) A) and B)
G) All of the above

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Medical professionals actually observe MDR-TB patients take their medicine through a program called DOT.

A) True
B) False

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The highest incidence of histoplasmosis in the United States occurs in the ________.


A) Southeast
B) Southwest
C) East and Midwest
D) Northeast
E) Rocky Mountains

F) A) and E)
G) C) and E)

Correct Answer

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Hantavirus has all of the following characteristics except ________.


A) a reservoir is human carriers
B) it is a zoonotic infection
C) the symptoms are abrupt fever,lung edema,respiratory distress,and hypotension
D) it is transmitted by aerosol transmission from rodent excreta
E) the first U.S.outbreak occurred in 1993 in the Southwest

F) B) and E)
G) B) and C)

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Secondary bacterial infections may occur with the common cold.

A) True
B) False

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Antigenic drift differs from antigenic shift in that antigenic drift reflects the exchange of RNA strands between different virus strains within a common host cell,whereas antigenic shift is the gradual mutation over time of the glycoproteins on the viral envelope that bind to immune cells.

A) True
B) False

Correct Answer

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Tuberculin skin testing ________.


A) injects PPD intradermally
B) uses a purified protein filtrate of Mycobacterium tuberculosis
C) will be positive if the person has had previous exposure to TB
D) will be positive if the person has active TB
E) All of the choices are correct.

F) All of the above
G) None of the above

Correct Answer

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Which of the following pairs of defense mechanisms is mismatched?


A) Complement activation - third line of defense
B) Ciliated epithelium - first line of defense
C) Secretory IgA - third line of defense
D) Antimicrobial peptides - second line of defense
E) Coughing - first line of defense

F) A) and E)
G) B) and C)

Correct Answer

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A

The causative organism of whooping cough is ________.


A) Bordetella pertussis
B) Streptococcus pneumoniae
C) Haemophilus influenzae
D) Streptococcus pyogenes
E) Corynebacterium diphtheriae

F) A) and D)
G) B) and D)

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Formation of a pseudomembrane in the back of the throat is seen in ________.


A) diphtheria
B) pharyngitis
C) tuberculosis
D) pertussis
E) SARS

F) C) and E)
G) A) and E)

Correct Answer

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Diphtherotoxin targets cells in the ________.


A) pharynx and lungs
B) lungs and heart
C) heart and brain
D) heart and nerves
E) lungs and nerves

F) A) and D)
G) A) and C)

Correct Answer

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Superantigens ________.


A) include streptolysin O
B) include erythrogenic toxin
C) induce production of tumor necrosis factor
D) can initiate a cascade of immune responses
E) All of the choices are correct.

F) B) and E)
G) B) and C)

Correct Answer

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